[國考] 醫學二 62題
61 有關succimer之敘述中，下列何者正確？
猨(A)又名DMPS（dimercaptopropanesulfornic acid）
獏(B)要以肌肉注射給藥
獱(C)可用於治療小孩之血中高鉛濃度
斅(D)會有高血壓之副作用
Basic & Clinical Pharmacology, 11th Edition
Bertram G. Katzung, Susan B. Masters, Anthony J. Trevor
Chapter 57. Heavy Metal Intoxication & Chelators >
我是從電子書裡找到的:
Since 1991, the Centers for Disease Control and Prevention (CDC) has
recommended chelation for all children with blood lead concentrations of 45
mcg/dL or greater. However, a recent randomized, double-blind,
placebo-controlled clinical trial of succimer in children with blood lead
concentrations between 25 mcg/dL and 44 mcg/dL found NO BENEFIT on
neurocognitive function or long-term blood lead reduction. Prophylactic use
of chelating agents in the workplace should never be a substitute for
reduction or prevention of excessive exposure.
因此應該為本題無正確答案，一律給分
可是血中的高鉛濃度是多高呢?
裡面還有其他我覺得有機會的,但我這幾天有事情不會上網,麻煩大家了
https://skydrive.live.com/#cid=EA0573AAB235B6A3&id=EA0573AAB235B6A3%21362
skydrive裡的國考申覆
感謝!
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