[申覆] 醫學一 61
有關細菌DNA複製的敘述，下列哪一項錯誤?
A.可由不特定的序列開始
B.可從多個起始點開始
C.有不同的機制並可雙向進行
D.是由多種DNA polymerases來負責
答案給A
不過我記得原核生物的起始點只有一個吧~~
因為手邊沒資料 查了一下WIKI
As DNA synthesis continues, the original DNA strands continue to unwind on
each side of the bubble, forming a replication fork with two prongs. In
bacteria, which have a "single origin" of replication on their circular
chromosome, this process eventually creates a "theta structure" (resembling
the Greek letter theta: θ). In contrast, eukaryotes have longer linear
chromosomes and initiate replication at multiple origins within these.
所以 A和B都算錯吧 建議都給分
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下載到了Lehninger Principles of Biochemistry,(4th ed.)的電子書~~
partIII 25 DNA metabolism
節錄The E. coli replication origin, oriC, consists of 245 bp;
原核生物此書只有舉E.coli，不過就只有一個Ori C
而在25.1 文末的Summary最後幾點也有說
Replication of the E. coli chromosome involves
many enzymes and protein factors organized in
replication factories, in which template DNA is
spooled through two replisomes tethered to the
bacterial plasma membrane.
Replication is similar in eukaryotic cells, but
eukaryotic chromosomes have many replication
origins.
都有強調E.coli也就是原核生物，只有一個起始點。
所以選A或B都可給分!!!!~
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