Re: 請問leptin(瘦體素)
※ 引述《mickeyya@kkcity.com.tw ()》之銘言:
: ※ 引述《mickeyya》之銘言:
: > 那請問..有沒有文章已經明確指出LEPTIN與肥胖的調節沒有顯著關係的呢??
: > 謝謝.. ^ ^a
: 可是我始終找不到單純研究LEPTIN與體重相關的文章 > < 很頭大壓..
Auwerx, J. & Staels, B. (1998) Leptin. Lancet 351, 737–742.
Brief overview of the leptin system and JAK-STAT signal
transductions.
Elmquist, J.K., Maratos-Flier, E., Saper, C.B., & Flier, J.S.
(1998) Unraveling the central nervous system pathways underlying
responses to leptin. Nat. Neurosci. 1, 445–450.
Short, excellent review.
Flier, J.S. & Maratos-Flier, E. (1998) Obesity and the
hypothalamus: novel peptides for new pathways. Cell 92, 437–440.
Freake, H.C. (1998) Uncoupling proteins: beyond brown adipose
tissue. Nutr. Rev. 56, 185–189.
Review of the structure, function, and role of uncoupling
proteins.
Friedman, J.M. (2002) The function of leptin in nutrition, weight,
and physiology. Nutr. Rev. 60, S1–S14.
Intermediate-level review of all aspects of leptin biology.
Inui, A. (1999) Feeding and body-weight regulation by
hypothalamic neuropeptides—mediation of the actions of leptin.
Trends Neurosci. 22, 62–67.
Short, intermediate-level review of the leptin system.
Jequier, E. & Tappy, L. (1999) Regulation of body weight in
humans. Physiol. Rev. 79, 451–480.
Detailed review of the role of leptin in body-weight regulation,
the control of food intake, and the roles of white and brown
adipose tissues in energy expenditure.
reference: Lehninger biochemistry 4/e page.918
另外Lehninger biochemistry chapter 23.4 也有提到Leptin的相關機制
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