PTT職涯區 / Biotech (生命科學)

[閒聊] 系統生物學研究

看板Biotech (生命科學)作者 (創造永遠的榮耀)時間16年前 (2010/03/18 20:25), 編輯推噓9(9推 0噓 36→)
留言45則, 5人參與, 最新討論串1/2 (看更多)
請問有在進行系統生物學研究的前輩 在這領域做的研究有需要配合實際上拿pipette做實驗的數據才能發PAPER嗎? 或是只要進行模擬、運算、程式跑出來或分析出來的資料就足夠了? 請各位在這領域上的前輩指教，謝謝! -- ※ 發信站: 批踢踢實業坊(ptt.cc) ◆ From: 120.126.49.164
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03/18 20:43, , 1F
看你的Lab有多"乾"
03/18 20:43, 1F
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03/18 21:51, , 2F
純乾也能有paper, 搭配實驗驗證點數更高
03/18 21:51, 2F
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03/18 21:52, , 3F
畢竟生物變化很大 純乾的東西證據力很薄弱
03/18 21:52, 3F
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03/18 21:54, , 4F
問者應該是要問純乾也能生存嗎? 我想應該也有生存空間吧
03/18 21:54, 4F
推
03/19 00:05, , 5F
Bioinformatic,BMC Bioinformatic, Nucleci Acid Resear
03/19 00:05, 5F
推
03/19 07:05, , 6F
沒做實驗單跑模擬的 systems biology 都是虎爛騙人的..
03/19 07:05, 6F
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03/19 07:06, , 7F
sysbio 搞了這麼多年拿了這麼多錢還是在那邊問一樣的問題
03/19 07:06, 7F
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03/19 07:07, , 8F
noise, robustness, bimodality.........
03/19 07:07, 8F
推
03/19 08:02, , 9F
是可以 不過應該大多還是會找各lab合作一邊幫你驗證
03/19 08:02, 9F
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03/19 13:50, , 10F
我覺得純乾也有他存在的價值 畢竟能整理一些東西給人參考
03/19 13:50, 10F
推
03/19 14:21, , 11F
then it's not systems BIOLOGY.
03/19 14:21, 11F
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03/19 14:22, , 12F
systems biology is not bioinformatics/biomaths.
03/19 14:22, 12F
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03/19 15:28, , 13F
xx學的定義離題了吧 啥學的定義寬廣如何實用是一回事
03/19 15:28, 13F
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03/19 15:28, , 14F
只碰電腦做生物能不能活下去 是比較實際的問題
03/19 15:28, 14F
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03/19 15:29, , 15F
就算是wet lab的東西絕大部分也都不實用 甚至更燒錢
03/19 15:29, 15F
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03/19 15:30, , 16F
架個電腦做研究其實相對簡單省錢很多
03/19 15:30, 16F
推
03/19 16:37, , 17F
簡單省錢是一回事, 但不碰實驗的東西不叫 systems biology
03/19 16:37, 17F
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03/19 16:38, , 18F
只是圈外人拿經費的手段而已. a model with no power to
03/19 16:38, 18F
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03/19 16:39, , 19F
predict is simply crap.
03/19 16:39, 19F
推
03/19 16:45, , 20F
"不碰實驗的東西不叫 systems biology" 確定這句話是對的?
03/19 16:45, 20F
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03/19 16:46, , 21F
系統生物的定義有這麼狹隘嗎?
03/19 16:46, 21F
推
03/19 16:47, , 22F
you have no way to understand the system without testing
03/19 16:47, 22F
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03/19 16:48, , 23F
it.. that is why power to predict is crucial. you can
03/19 16:48, 23F
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03/19 16:48, , 24F
generate all kinds of ode models you like.. but if that
03/19 16:48, 24F
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03/19 16:48, , 25F
是啊 但是每個人可以負責專長 都碰電腦 實驗交給擅長的人做
03/19 16:48, 25F
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03/19 16:49, , 26F
only happens in vitural world or under extreme conditions
03/19 16:49, 26F
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03/19 16:49, , 27F
, that is crap.
03/19 16:49, 27F
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03/19 16:49, , 28F
取別人的數據來分析 或是自己分析交給別人實驗 各盡專長
03/19 16:49, 28F
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03/19 16:51, , 29F
現在已經累積一對各種array 的資列庫
03/19 16:51, 29F
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03/19 16:51, , 30F
單純拿別人的資料庫來分析 一樣有意義
03/19 16:51, 30F
推
03/19 16:52, , 31F
then again, if you are doing bioinfomatics, that's not
03/19 16:52, 31F
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03/19 16:52, , 32F
sysbio. you might be survive by staying dry, but at the
03/19 16:52, 32F
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03/19 16:53, , 33F
same time you are not doing sysbio.
03/19 16:53, 33F
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03/19 16:53, , 34F
ok 你的定義真嚴謹
03/19 16:53, 34F
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03/19 16:53, , 35F
if you want to do sysbio, the real one, you have to get
03/19 16:53, 35F
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03/19 16:54, , 36F
your hands wet. dry work only is not enough.
03/19 16:54, 36F
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03/19 16:55, , 37F
"負責系統生物的乾部分" 這樣也不行喔...
03/19 16:55, 37F
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03/19 16:55, , 38F
so by doing molecular cloning, can you label yourself a
03/19 16:55, 38F
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03/19 16:56, , 39F
systems biologist?
03/19 16:56, 39F
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03/19 16:56, , 40F
back to the very beginning question "if that's enough?"
03/19 16:56, 40F
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03/19 16:56, , 41F
I think the answer is no if you are talking about sysbio.
03/19 16:56, 41F
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03/19 16:57, , 42F
那要看實驗室的規模啊 如果實驗是真有那樣的規模
03/19 16:57, 42F
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03/19 16:57, , 43F
但我只負責cloning 我還是能說我有參與系統生物學的研究
03/19 16:57, 43F
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03/19 16:59, , 44F
= = 好吧 我對系統生物這個辭沒研究 不跟你強辯了
03/19 16:59, 44F
推
03/19 16:59, , 45F
I disagree but respect your view on this..just my 2 cents
03/19 16:59, 45F
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