Re: [新聞] 「宇昌案」特偵簽結 查無不法
看板Bioindustry (生物科技)作者puec2 (don't argue with idiot)時間12年前 (2012/08/15 21:55)推噓9(17推 8噓 149→)留言174則, 14人參與討論串4/7 (看更多)
http://www.natap.org/2009/HIV/012809_01.htm
TNX-355 survives Tanox: new Phase 2 Dose-Finding StudyStudy
Genentech license launches new team at TaiMed Biologics
New TNX-355 Phase 2 Dose-Finding Study (IV administration evert 2
or 4 weeks)
http://clinicaltrials.gov/ct2/show/NCT00784147?term=HIV+
Houston&recr=Open&rank=6
April 2008
Houston Business Journal -
by Mary Ann Azevedo Houston Business Journal
Dr. Stanley Lewis of TaiMed Biologics: Keeping clinical trials in
Houston with financial support from the government of Taiwan.
A promising HIV/AIDS treatment drug formerly in the Tanox Inc.
fold remains in the Houston pipeline.
TaiMed Biologics Inc. will conduct clinical trials of TNX-355 --
also known as Ibalizumab -- from a location on the West Loop near
the former Tanox headquarters in suburban Bellaire.
The newly formed subsidiary of Taiwan-based TaiMed Inc. is funded
in part by the government of Taiwan.
The scientific founder of TaiMed Biologics is famed AIDS
researcher Dr. David Ho, who briefly served on Tanox's scientific
advisory board and was Time magazine's 1996 Man of the Year.
Genentech Inc. licensed Ibalizumab to TaiMed Biologics after
acquiring Tanox for $919 million and moving the company to
California last year.
The San Francisco-based biotech giant bought Tanox primarily for
rights to Xolair, a well-known drug used in treating asthma.
Under the new licensing agreement, TaiMed Biologics is moving full
speed ahead on development of Ibalizumab.
Dr. Stanley Lewis, vice president and chief medical officer of
TaiMed Biologics, says the company will put the drug through a new
phase of trials sometime in the first half of this year.
Lewis is one of five former Tanox employees now on the TaiMed
Biologics payroll.
The company's U.S. office is essentially virtual. CEO James Chang
works out of Irvine, Calif., and other management team members are
in San Diego and New York City. Ho, scientific founder of the
company, currently serves as CEO of the New York City-based Aaron
Diamond AIDS Research Center.
TaiMed Biologics is part of a major collaboration between
government and the private sector to build the biotechnology
industry in Taiwan. The company receives support through the $62
billion National Development Fund of Taiwan.
The fund has earmarked $200 million for biotechnology, and has
agreed to invest 40 percent of the capital required by TaiMed
Biologics.
Ing-wen Tsai, chairman of TaiMed Inc. and a former vice premier of
Taiwan, describes pursuit of the commercialization of Ibalizumab
as "a major push to kick off the momentum of this industry in
Taiwan."
Genentech also serves as a minority investor in TaiMed Biologics.
Asthma attraction
Genentech's main objective in acquiring Tanox was to increase
profitability in the asthma drug market.
The company had a three-way agreement with Tanox and Novartis
Pharmaceuticals on Xolair.
Genentech spokeswoman Caroline Pecquet explains the acquisition
strategy.
By acquiring Tanox, she says, Genentech was able "to eliminate
U.S. royalty obligations to Tanox on Xolair and obtain
Novartis' U.S. and ex-U.S. profit share and royalty payments to
Tanox."
AIDS therapy didn't fit into Genentech's three primary areas of
research -- oncology, immunology and tissue growth and repair. So
the firm decided to license out Ibalizumab to a company with
specific expertise in HIV.
The licensing agreement gives TaiMed Biologics exclusive rights to
develop and commercialize the drug and other anti-CD4 monoclonal
antibodies in exchange for undisclosed up front, milestone and
royalty payments.
--
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