Re: Promoter SNPs

看板Biology (生物學)作者amfitrionas.時間19年前 (2006/10/05 13:01)推噓0(0推 0噓 0→)

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On Thu, 05 Oct 2006 07:42:37 +0300, VP <amfitrionasNOSPAM@yahoo.gr> wrote: 1) How about this method: I went here: www.pubmed.com and I have chosen the GENE database. Let's say I was interested at the VWF promoter gene polymorphisms. I typed VWF itno the search box and it gave me the VWF gene information for several organisms. I chose HOMO SAPIENS, but not the gene itself but the word links at the top right of the name of the gene. Then I chose GeneViewIndbSNP and it gave me all the SNPs for the VWF gene, here: http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=7450. At the bottom of this page there are 11 SNPs, TO THE GENOMIC REGION NEAR THE VWF GENE. My question is: ARE THESE SNPs PROMOTER SNPs? 2) I have also found this: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1361283 Is it worth trying? I tried it and it gave me a dead link. 3) Another question: If you have the RS number for a given SNP, is there an easy way to find if this is a promoter SNP? >>Here is the thing: >> >>I search here >>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=snp >> >>for SNPs that concern the promoter of several genes. >> >>My question is: >> >>1) Am I searching iat the right place, or should I try here: >>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed ? >> >>2) If this is the right place >>(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=snp) >> >>which option should I use from the "limits" section in order to take >>as results only the "promoter SNPs"? >> >>3) If this is not the right place >>(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=snp) >> >>where and under which keywords or limits should I search? >> >>Thanks in advance