[申覆] 醫學六 31
看板medstudent (醫學生)作者chihuahua (chihuahua)時間15年前 (2010/08/04 01:09)推噓10(10推 0噓 0→)留言10則, 9人參與討論串1/5 (看更多)
[申覆] 醫學六 31
答案: B.懷孕前服用葉酸及多種維生素,懷孕後接受高層次超音波檢查
這答案好像已經把etiology設定為:Folic acid deficiency
其它的etiology也包括了:Genetic factors
-->那麼D也應該是答案之一
Genetic factors — A genetic factor is suggested by the observations that
NTDs have a high concordance rate in monozygotic twins, are more frequent
among siblings, and are more common in females compared to males [9].
In addition, there is a high prevalence of karyotypic abnormalities among
fetuses with NTDs, especially in the presence of other congenital anomalies.
For example, a large study evaluating the frequency of chromosomal
abnormalities in pregnancies with fetal NTDs found these abnormalities in
6.5 percent of affected cases (4/167 fetuses with an isolated NTD and 9/33
fetuses with a NTD and associated anomalies) [10]. A second series reported
a similar rate (7 percent) of chromosomal abnormalities in fetuses with NTDs
[11]. Trisomy 18 was the most common aneuploidy in both series. These data
support the use of fetal karyotyping as an aid in diagnostic
evaluation and recurrence risk counseling.
資料來源: Uptodate.com - Anencephaly and encephalocele
建議B,D皆給分
覆議的請推文 謝謝
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